ALNYLAM PHARMACEUTICALS INC

NASDAQ: ALNY (Alnylam Pharmaceuticals, Inc.)

Last update: 16 hours ago

471.14

-2.15 (-0.45%)

Previous Close 473.29
Open 472.67
Volume 399,550
Avg. Volume (3M) 1,096,587
Market Cap 62,244,106,240
Price / Earnings (TTM) 1,682.64
Price / Earnings (Forward) 53.48
Price / Sales 19.59
Price / Book 267.34
52 Weeks Range
205.87 (-56%) — 495.55 (5%)
Earnings Date 30 Oct 2025
Profit Margin -11.49%
Operating Margin (TTM) 3.04%
Diluted EPS (TTM) -2.11
Quarterly Revenue Growth (YOY) 20.20%
Total Debt/Equity (MRQ) 2,358.25%
Current Ratio (MRQ) 3.04
Operating Cash Flow (TTM) -45.11 M
Levered Free Cash Flow (TTM) 223.09 M
Return on Assets (TTM) -1.79%

Market Trend

Short Term Medium Term
Industry Biotechnology (US) Mixed Mixed
Biotechnology (Global) Mixed Mixed
Stock Alnylam Pharmaceuticals, Inc. Bullish Bullish

AIStockmoo Score

1.0
Analyst Consensus 1.5
Insider Activity -3.0
Price Volatility -0.5
Technical Moving Averages 5.0
Technical Oscillators 2.0
Average 1.00

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Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway within cells for sequence-specific silencing and regulation of gene expression. Alnylam has five drugs on the market: Onpattro and Amvuttra for hATTR amyloidosis, Givlaari for acute hepatic porphyria, Oxlumo for primary hyperoxaluria type 1, and Leqvio for hypercholesterolemia. It also has several clinical programs across various therapeutic areas: genetic medicines; cardio-metabolic diseases; hepatic infectious diseases, and CNS/ocular diseases. Upfront fees from research partnerships have boosted Alnylam's cash levels, and the company stands to see additional milestones and royalties from drugs commercialized under collaboration partnerships.

Sector Healthcare
Industry Biotechnology
Investment Style Mid Core
% Held by Insiders 3.81%
% Held by Institutions 97.56%
52 Weeks Range
205.87 (-56%) — 495.55 (5%)
Price Target Range
470.00 (-0%) — 570.00 (20%)
High 570.00 (HC Wainwright & Co., 20.98%) Buy
Median 507.53 (7.72%)
Low 470.00 (BMO Capital, -0.24%) Buy
Average 511.65 (8.60%)
Total 12 Buy, 2 Hold
Avg. Price @ Call 458.20
Firm Date Target Price Call Price @ Call
Wells Fargo 11 Nov 2025 479.00 (1.67%) Hold 451.95
Barclays 31 Oct 2025 527.00 (11.86%) Buy 456.04
Piper Sandler 31 Oct 2025 489.00 (3.79%) Buy 456.04
Jefferies 30 Oct 2025 549.00 (16.53%) Buy 449.56
Truist Securities 17 Oct 2025 535.00 (13.55%) Buy 481.67
JP Morgan 13 Oct 2025 473.00 (0.39%) Buy 464.95
HC Wainwright & Co. 10 Oct 2025 570.00 (20.98%) Buy 460.46
Morgan Stanley 06 Oct 2025 475.00 (0.82%) Hold 452.00
Stifel 06 Oct 2025 495.00 (5.06%) Buy 452.00
RBC Capital 19 Sep 2025 500.00 (6.13%) Buy 453.56
B of A Securities 17 Sep 2025 520.00 (10.37%) Buy 451.73
Goldman Sachs 16 Sep 2025 566.00 (20.13%) Buy 461.24
Evercore ISI Group 11 Sep 2025 515.05 (9.32%) Buy 468.58
BMO Capital 08 Sep 2025 470.00 (-0.24%) Buy 455.03
Show more
Name Avg. Buy ($) Avg. Sell ($) Net Quantity Net Value ($)
GREENSTREET YVONNE - 445.12 -1,121 -498,980
Aggregate Net Quantity -1,121
Aggregate Net Value ($) -498,980
Aggregate Avg. Buy ($) -
Aggregate Avg. Sell ($) 445.12
Name Holder Date Type Quantity Price Value ($)
GREENSTREET YVONNE Officer 26 Nov 2025 Disposed (-) 1,121 445.12 498,980
GREENSTREET YVONNE Officer 26 Nov 2025 Option execute 4,697 - -

The support, resistance and trendline levels presented has been generated by an artificial intelligence (AI) model and should be interpreted with caution.

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