ALNYLAM PHARMACEUTICALS INC

NASDAQ: ALNY (Alnylam Pharmaceuticals, Inc.)

Last update: 4 days ago, 9:13AM

244.40

0.41 (0.17%)

Previous Close 243.99
Open 242.70
Volume 41,166
Avg. Volume (3M) 768,953
Market Cap 31,522,955,264
Price / Sales 14.77
Price / Book 972.68
52 Weeks Range
141.98 (-41%) — 304.39 (24%)
Earnings Date 13 Feb 2025 - 17 Feb 2025
Profit Margin -15.86%
Operating Margin (TTM) -15.35%
Diluted EPS (TTM) -2.61
Quarterly Revenue Growth (YOY) -33.30%
Total Debt/Equity (MRQ) 8,426.14%
Current Ratio (MRQ) 2.75
Operating Cash Flow (TTM) 56.55 M
Levered Free Cash Flow (TTM) 309.57 M
Return on Assets (TTM) -2.92%

Market Trend

Short Term Medium Term
Industry Biotechnology (US) Mixed Mixed
Biotechnology (Global) Mixed Mixed
Stock Alnylam Pharmaceuticals, Inc. Bullish Bullish

AIStockmoo Score

-0.2
Analyst Consensus 1.5
Insider Activity -1.5
Price Volatility 2.0
Technical Moving Averages -2.5
Technical Oscillators -0.5
Average -0.20

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Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway within cells for sequence-specific silencing and regulation of gene expression. Alnylam has five drugs on the market: Onpattro and Amvuttra for hATTR amyloidosis, Givlaari for acute hepatic porphyria, Oxlumo for primary hyperoxaluria type 1, and Leqvio for hypercholesterolemia. It also has several clinical programs across various therapeutic areas: genetic medicines; cardio-metabolic diseases; hepatic infectious diseases, and CNS/ocular diseases. Upfront fees from research partnerships have boosted Alnylam's cash levels, and the company stands to see additional milestones and royalties from drugs commercialized under collaboration partnerships.

Sector Healthcare
Industry Biotechnology
Investment Style Mid Growth
% Held by Insiders 0.43%
% Held by Institutions 98.21%
52 Weeks Range
141.98 (-41%) — 304.39 (24%)
Price Target Range
220.00 (-9%) — 400.00 (63%)
High 400.00 (HC Wainwright & Co., 63.67%) Buy
Median 312.00 (27.66%)
Low 220.00 (Cantor Fitzgerald, -9.98%) Hold
Average 320.17 (31.00%)
Total 11 Buy, 1 Hold
Avg. Price @ Call 270.13
Firm Date Target Price Call Price @ Call
HC Wainwright & Co. 18 Nov 2024 400.00 (63.67%) Buy 232.27
04 Nov 2024 400.00 (63.67%) Buy 269.95
Piper Sandler 18 Nov 2024 296.00 (21.11%) Buy 232.27
Barclays 01 Nov 2024 329.00 (34.62%) Buy 273.91
Canaccord Genuity 01 Nov 2024 384.00 (57.12%) Buy 273.91
Chardan Capital 01 Nov 2024 300.00 (22.75%) Buy 273.91
11 Oct 2024 300.00 (22.75%) Buy 284.32
Needham 01 Nov 2024 320.00 (30.93%) Buy 273.91
10 Oct 2024 320.00 (30.93%) Buy 278.62
RBC Capital 01 Nov 2024 300.00 (22.75%) Buy 273.91
10 Oct 2024 300.00 (22.75%) Buy 278.62
Raymond James 01 Nov 2024 298.00 (21.93%) Buy 273.91
Scotiabank 01 Nov 2024 310.00 (26.84%) Buy 273.91
16 Oct 2024 305.00 (24.80%) Buy 300.55
TD Cowen 21 Oct 2024 371.00 (51.80%) Buy 292.01
B of A Securities 14 Oct 2024 314.00 (28.48%) Buy 283.32
Cantor Fitzgerald 11 Oct 2024 220.00 (-9.98%) Hold 284.32
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Name Avg. Buy ($) Avg. Sell ($) Net Quantity Net Value ($)
GARG PUSHKAL - 245.26 -1,752 -429,696
Aggregate Net Quantity -1,752
Aggregate Net Value ($) -429,696
Aggregate Avg. Buy ($) -
Aggregate Avg. Sell ($) 245.26
Name Holder Date Type Quantity Price Value ($)
GARG PUSHKAL Officer 12 Dec 2024 Automatic sell (-) 1,752 245.26 429,696
Date Type Details
27 Nov 2024 Announcement Alnylam to Webcast Presentation at Piper Sandler 36th Annual Healthcare Conference
25 Nov 2024 Announcement Alnylam Announces U.S. Food and Drug Administration Acceptance of Supplemental New Drug Application for Vutrisiran for the Treatment of ATTR Amyloidosis with Cardiomyopathy
17 Nov 2024 Announcement Alnylam Announces Interim Phase 1 Data of Nucresiran (ALN-TTRsc04) Showing Rapid Knockdown of TTR that is Sustained at Six Months Following a Single Dose
04 Nov 2024 Announcement Alnylam to Webcast Presentations at Upcoming November Investor Conferences
31 Oct 2024 Announcement Alnylam Pharmaceuticals Reports Third Quarter 2024 Financial Results and Highlights Recent Period Activity
30 Oct 2024 Announcement Alnylam to Showcase Latest Data from TTR Franchise and Hypertension Program at American Heart Association Scientific Sessions 2024
17 Oct 2024 Announcement Alnylam to Webcast Conference Call Discussing Third Quarter 2024 Financial Results
16 Oct 2024 Announcement Alnylam Submits Regulatory Application to the European Medicines Agency for Vutrisiran for the Treatment of ATTR Amyloidosis with Cardiomyopathy
09 Oct 2024 Announcement Alnylam Submits Supplemental New Drug Application (sNDA) to the U.S. Food and Drug Administration for Vutrisiran for the Treatment of Transthyretin Amyloidosis with Cardiomyopathy
29 Sep 2024 Announcement Alnylam Highlights New Data From HELIOS-B Study of Vutrisiran for the Treatment of Transthyretin Amyloidosis With Cardiomyopathy at Heart Failure Society of America Annual Scientific Meeting 2024
26 Sep 2024 Announcement Alnylam to Webcast TTR Investor Day
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